Cloridrato di 5-MeO-DiPT
Cloridrato di 5-MeO-DiPT Fascia di prezzo: da €23.50 a €336.00
Torna ai prodotti
Fumarato di EPT (N-etil-N-propiltriptamina)
Fumarato di EPT (N-etil-N-propiltriptamina) Fascia di prezzo: da €23.50 a €336.00
5-MeO-DMT hydrochloride - immagine 1
5-MeO-DMT hydrochloride - immagine 2

Cloridrato di 5-MeO-DMT

5-MeO-DMT hydrochloride properties

Sinonimo: Cloridrato di 5-metossi-N,N-dimetiltriptamina
Numero CAS: Dopo
Formula: Cloridrato di 3-[2-(dimetilammino)etil]-5-metossindolo
Massa molare: 254,8 g/mol
Purezza: >97%

Fascia di prezzo: da €25.00 a €360.00

Aggiungi al confronto
Aggiungi alla lista dei desideri
RISPARMIA 15%

altri 2 prodotti

RISPARMIA 50%

6 al prezzo di 3

* Le informazioni contenute in questa pagina sono un riassunto e non intendono coprire tutte le informazioni disponibili su questo farmaco. Non coprono tutti i possibili usi, le indicazioni, le precauzioni, le interazioni farmacologiche o gli effetti avversi e non sostituiscono la competenza e il giudizio del vostro medico.

5-MeO-DMT Hydrochloride – Scientific Product Documentation

Descrizione generale

5-MeO-DMT hydrochloride (5-Methoxy-N,N-dimethyltryptamine HCl) is a water-soluble salt of classical tryptamine, particularly suitable for pharmacological research due to its increased stability and bioavailability compared to the freebase form.

Specifiche tecniche

ParametroSpecification
Chemical FormulaC₁₃H₁₈N₂O · HCl
Molecular Weight254.75 g/mol
Purezza≥98% (analyzed by HPLC-UV)
AspettoWhite to light yellow crystalline powder
SolubilityHigh in water (>50 mg/ml), methanol, PBS
Melting point243-247°C (decomposes)
StabilitàHygroscopic; store in dry conditions

Applicazioni scientifiche

1. Neuropharmacology & Behavioral Research

  • Serotonin receptor studies:  Potent 5-HT₁ₐ/₂ₐ agonist with rapid cerebral penetration.

  • Animal experiments (in vivo):  Behavioural paradigms (e.g. head-twitch response in rodents).

  • Electrophysiology:  Effects on neuronal oscillations (e.g., gamma-band activity).

2. Biochemical & Molecular Studies

  • Intracellular signaling:  cAMP accumulation and β-arrestin recruitment assays.

  • Enzyme kinetics:  MAO-A metabolism (IC₅₀ ~2-5 μM).

3. Clinically Relevant Research

  • Dose-response relationships:  Preclinical safety profiling.

  • Comparative pharmacology:  Towards psilocybin, DMT, and other tryptamines.

Experimental Guidelines

Recommended Concentrations

ApplicazioneConcentration rangeSolvente
Cell cultures (in vitro)1 nM – 10 μMPBS/DMEM (≤0.1% DMSO)
Receptor assays0.1 – 100 μMTris-HCl buffer (pH 7.4)
Animal studies (ip/iv)0.1 – 5 mg/kgSterile saline solution

Misure di sicurezza

  • Personal protection:  Lab coat, gloves (nitrile), safety glasses.

  • Gestione:  Hygroscopic – close promptly after use.

  • Storage:  Airtight, under argon, at -20°C (prevent hydrolysis).

Stability & Storage

  • Shelf life:

    • -20°C:  >2 years (unchanged purity).

    • 4°C:  6 months (in dry environment).

  • Relegation:

    • Hydrolysis on prolonged exposure to moisture (monitor by HPLC).

Analytical Validation

Each batch comes with:

  1. Cromatogramma HPLC-UV  (C18 column, retention time ~6.2 min).

  2. MS/MS fragmentation  (characteristic ions: m/z 219 → 174, 160).

  3. Residual solvents  (meet ICH Q3C guidelines).

Legal Status (Netherlands/EU)

  • Narcotics legislation:  Not explicitly mentioned in the Opium Act, but possibly under analogous legislation (Appendix II).

  • Scientific use:  Permit required for institutions (CCMO approval for animal testing).

  • Export control:  Subject to EU Regulation 2019/1998 (psychotropic substances).

Domande frequenti (FAQ)

Q1 : What are the advantages of HCl over freebase?

  • Improved solubility  (ideal for injection studies).

  • Longer shelf stability  at room temperature.

Q2: Is 5-MeO-DMT-HCl detectable in drug tests?
A: Yes, via:

  • LC-MS/MS  (recognized as 5-MeO-DMT + HCl adduct).

  • Immunoassays:  Cross-reactivity with DMT (~15-20%).

Q3: Are there risks when combining with MAO inhibitors?
UN:  Absolutely.

  • Increased risk of  serotonin syndrome  (avoid combination!).

  • Use only in MAO-free models.

Q4: How to dispose of waste?
UN:

  1. Neutralize with  sodium bicarbonate  (pH 7-8).

  2. Adsorb with  activated carbon .

  3. Dispose of as  hazardous chemical waste  (UN 3249, Class 6.1).

References & Contact

Core literature:

  1. Shen et al. (2010). “Pharmacology of 5-MeO-DMT derivatives”.  J Psychopharmacol .

  2. Kaasik et al. (2021). “Metabolic pathways of 5-MeO-DMT”.  Xenobiotics .

This product is intended only for authorized scientific research. Not for human consumption or diagnostic use. Please observe local regulations.