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5-MeO-DMT hydrochloride - Mynd 1
5-MeO-DMT hydrochloride - Mynd 2

5-MeO-DMT hýdróklóríð

5-MeO-DMT hydrochloride properties

Samheiti: 5-metoxý-N,N-dímetýltryptamínhýdróklóríð
CAS-númer: eftir
Formúla: 3-[2-(dímetýlamínó)etýl]-5-metoxýindólhýdróklóríð
Mólmassi: 254,8 g/mól
Hreinleiki: >97%

Verðbil: €25.00 til €360.00

Bæta við til að bera saman
Bæta við óskalista
SPARAÐU 15%

fleiri 2 vörur

SPARA 50%

6 á verði 3

* Upplýsingarnar á þessari síðu eru samantekt og eru ekki ætlaðar til að ná yfir allar tiltækar upplýsingar um þetta lyf. Þær fjalla ekki um alla mögulega notkun, leiðbeiningar, varúðarráðstafanir, milliverkanir lyfja eða aukaverkanir og koma ekki í stað sérfræðiþekkingar og mats heilbrigðisstarfsmanns.

5-MeO-DMT Hydrochloride – Scientific Product Documentation

General Description

5-MeO-DMT hydrochloride (5-Methoxy-N,N-dimethyltryptamine HCl) is a water-soluble salt of classical tryptamine, particularly suitable for pharmacological research due to its increased stability and bioavailability compared to the freebase form.

Tæknilegar upplýsingar

FæribreytaUpplýsingar
Chemical FormulaC₁₃H₁₈N₂O · HCl
Molecular Weight254,75 g/mól
Hreinleiki≥98% (analyzed by HPLC-UV)
ÚtlitHvítt til ljósgult kristallað duft
LeysniHigh in water (>50 mg/ml), methanol, PBS
Bræðslumark243-247°C (decomposes)
StöðugleikiHygroscopic; store in dry conditions

Vísindaleg notkun

1. Neuropharmacology & Behavioral Research

  • Serotonin receptor studies:  Potent 5-HT₁ₐ/₂ₐ agonist with rapid cerebral penetration.

  • Animal experiments (in vivo):  Behavioural paradigms (e.g. head-twitch response in rodents).

  • Electrophysiology:  Effects on neuronal oscillations (e.g., gamma-band activity).

2. Biochemical & Molecular Studies

  • Intracellular signaling:  cAMP accumulation and β-arrestin recruitment assays.

  • Enzyme kinetics:  MAO-A metabolism (IC₅₀ ~2-5 μM).

3. Clinically Relevant Research

  • Dose-response relationships:  Preclinical safety profiling.

  • Comparative pharmacology:  Towards psilocybin, DMT, and other tryptamines.

Experimental Guidelines

Recommended Concentrations

UmsóknConcentration rangeLeysiefni
Cell cultures (in vitro)1 nM – 10 μMPBS/DMEM (≤0,1% DMSO)
Receptor assays0,1 – 100 míkrómólTris-HCl stuðpúði (pH 7,4)
Animal studies (ip/iv)0,1 – 5 mg/kgSterile saline solution

Öryggisráðstafanir

  • Personal protection:  Lab coat, gloves (nitrile), safety glasses.

  • Meðhöndlun:  Hygroscopic – close promptly after use.

  • Geymsla:  Airtight, under argon, at -20°C (prevent hydrolysis).

Stability & Storage

  • Geymsluþol:

    • -20°C:  >2 years (unchanged purity).

    • 4°C:  6 months (in dry environment).

  • Relegation:

    • Hydrolysis on prolonged exposure to moisture (monitor by HPLC).

Analytical Validation

Each batch comes with:

  1. HPLC-UV litrófsgreining  (C18 column, retention time ~6.2 min).

  2. MS/MS fragmentation  (characteristic ions: m/z 219 → 174, 160).

  3. Leifar af leysiefnum  (meet ICH Q3C guidelines).

Legal Status (Netherlands/EU)

  • Narcotics legislation:  Not explicitly mentioned in the Opium Act, but possibly under analogous legislation (Appendix II).

  • Scientific use:  Permit required for institutions (CCMO approval for animal testing).

  • Útflutningseftirlit:  Subject to EU Regulation 2019/1998 (psychotropic substances).

Algengar spurningar (FAQ)

Q1 : What are the advantages of HCl over freebase?

  • Improved solubility  (ideal for injection studies).

  • Longer shelf stability  at room temperature.

Q2: Is 5-MeO-DMT-HCl detectable in drug tests?
A: Yes, via:

  • LC-MS/MS  (recognized as 5-MeO-DMT + HCl adduct).

  • Ónæmisprófanir:  Cross-reactivity with DMT (~15-20%).

Q3: Are there risks when combining with MAO inhibitors?
A:  Absolutely.

  • Increased risk of  serotonin syndrome  (avoid combination!).

  • Use only in MAO-free models.

Q4: How to dispose of waste?
A:

  1. Neutralize with  sodium bicarbonate  (pH 7-8).

  2. Adsorb with  activated carbon .

  3. Dispose of as  hazardous chemical waste  (UN 3249, Class 6.1).

References & Contact

Core literature:

  1. Shen o.fl. (2010). „Lyfjafræði 5-MeO-DMT afleiða“.  J Psychopharmacol .

  2. Kaasik o.fl. (2021). „Efnaskiptaferlar 5-MeO-DMT“.  Xenobiotics .

This product is intended only for authorized scientific research. Not for human consumption or diagnostic use. Please observe local regulations.